In eukaryotes, miR-5 is a microRNA with sequence complementarity to the 3’UTR of the mRNA transcript encoded by the UCD gene. The UCD gene encodes for a protein that acts as an allosteric activator of the protein p101. The p101 protein is a DNA methyltransferase (DNMT) which is an enzyme that methylates DNA when the protein is in its active form.
A) In a lung cancer cell line, the p101 protein is overly active leading to misregulation of gene expression. In these lung cancer cells which of the following would be a correct prediction in regards to miR-5? [choose ALL that apply, note that incorrect selections will deduct points]
A) The gene encoding miR-5 is in a region of chromatin with hypoacetylation
B) The gene encoding miR-5 is in a region of chromatin with hyperacetylation
C) The gene encoding miR-5 in a region of euchromatin
D) The gene encoding miR-5 in a region of heterochromatin
E) The miR-5 transcript is translated at high levels
F) The miR-5 transcript is activating translation of the UCD gene
B) A different lung cancer cell line is found to have significantly decreased amounts of DNA methylation. Which of the following could explain why there is decreased DNA methylation in this cell line? [choose ALL that apply, note that incorrect selections will deduct points]
A) increased amounts of the p101 protein due to low levels of miR-5
B) increased amounts of the UCD protein due to high levels of miR-5
C) decreased amounts of the UCD protein due to low levels of miR-5
D) the absence of the UCD protein due to miR-5 inhibiting translation of the UCD mRNA transcript
E) the absence of the p101 protein due to miR-5 inhibiting transcription of the p101 mRNA transcript

Answers

Answer 1

Answer:

A) A) The gene encoding miR-5 is in a region of chromatin with hypoacetylation.  

D) The gene encoding miR-5 in a region of heterochromatin.

B) D) the absence of the UCD protein due to miR-5 inhibiting translation of the UCD mRNA transcript

Explanation:

MicroRNAs (miRNAs) are small regulatory RNA sequences (approximately 20-24 nucleotides in length) that regulate gene expression by RNA interference (RNAi) mechanisms. These sequences (miRNAs) bind by base complementarity to messenger RNAs and thus inhibit protein translation and/or trigger mRNA degradation. In this case, miR-5 binds to the 3’UTR of the mRNA transcript of the UCD gene, thereby inhibiting/slowing protein UCD synthesis. The UCD protein is an allosteric regulator that binds and activates the expression of the p101 protein, thereby the miR-5 RNAi pathway also indirectly decreases the expression of the p101 gene. Moreover, hypoacetylation is an epigenetic mark generally associated with gene silencing (heterochromatin is a transcriptionally inactive state of chromatin).


Related Questions

When using a scientific calculator, what is the the correct order of buttons to
press to enter the number 3.5 x 1015?
O A. [EE] [1] [5] [3] [] [5]
B. [1] [5] [3] [5] [EE]
C. [3] [.] [5] [EE] [1] [5]
O D. [1] [5] [3] [] [5] [EE]
SUBMIT

Answers

It’s D because it had been multiple times the amount

An ecologist counted the number of eggs in randomly selected nests in a population of birds. To test the hypothesis that the number of eggs per nest follows a Poisson distribution at the 5% level of significance, you will need to compare a calculated value with a critical value.
Eggs Number of nests Prob Expected
nest, xi per fi
0 15 0.2845 19.9
1 29 0.3576 25.0
2 19 0.2248 15.7
23 7 0.1331 9.3
SUM: 70 1.0000 70.0
What are the calculated and critical values for this test?
a. calculated = 45.6; critical = 5.991.
b. calculated = 3.10; critical = 5.991.
c. calculated = 5.89; critical = 5.991.
d. calculated = 3.10; critical = 7.815.

Answers

Answer:

d. calculated = 3.10; critical = 7.815.

Explanation:

To test the hypothesis Given in the question above, we use the Chisquare goodness of fit :

The test statistic is defined as :

χ² = Σ(Observed - Expected)² / Expected

Observed = number of nests

χ² = ((15 - 19.9)^2 / 19.9) + ((29 - 25)^2 / 25) + ((19 - 15.7)^2 / 15.7) + ((7 - 9.3)^2 / 9.3)

χ² = 3.1089

The critical value :

df = n - 1 = 4 - 1 = 3

The critical value ;P(χ² at 0.05, df = 3 ) = 7.815

hey ,What is biological community answer it .Good night​

Answers

Answer:

Community, also called biological community, in biology, an interacting group of various species in a common location. For example, a forest of trees and undergrowth plants, inhabited by animals and rooted in soil containing bacteria and fungi, constitutes a biological community.

Explanation:

hope this helps you pls mark as brainliest

Answer:

It's a group of various species in a common place.

For example: a forest of trees and undergrowth plants,  lived in by animals and rooted in soil including bacteria and fungi, would make a biological community.

I hope this Helped!

What were the three large, flightless birds with similar features found on different continents, Australia, Africa, and South America?

Answers

Answer:

Rhea from south america

Emu from Australia

ostrich in Africa

Question Mode Fill in the Blank Question Fill in the blank question. In cells that contain a nucleus, the DNA is divided into multiple linear chromosomes which are organized into a complex structure called

Answers

Answer:

The correct answer is - chromatin.

Explanation:

Chromatin is a part within a chromosome consisting of DNA and protein. The DNA carries the cell's genetic instructions and these are complex structures present in multiple linear chromosomes.

The major proteins in chromatin are histones, which help package the DNA in a compact form that fits in the cell nucleus.

Which of the following statements is true about interacting with people from different cultures? O a) Most people within a culture think and act the same. O b) It's important to treat people from different cultures as individuals. Oc) Some cultures are better than other cultures. Generalizations and stereotypes don't impact people's perceptions of cultures.

Answers

Answer:

I hope it helps you

I think b is the answer

Bào tử sinh ra trong túi, khi chín, bào tử được giải phóng ra bên ngoài, là hình thức sinh sản bằng:
A. Bào tử đốt
C. Bào tử nang
D. Bào tử tiếp hợp
B. Bào tử đính

Answers

Bào tử sinh ra trong túi, khi chín, bào tử được giải phóng ra bên ngoài, là hình thức sinh sản bằng:

A. Bào tử đốt

C. Bào tử nang

D. Bào tử tiếp hợp

B. Bào tử đính

Nó sẽ là lựa chọn A và D nhưng nếu nó chỉ cho phép bạn một lựa chọn thì A.

Bởi vì các bào tử sinh sản và có một cách tự vệ và đó là bằng cách châm chích. Và có hàng ngàn bào tử trên khắp môi trường của chúng ta.

plz give a correct answer for the question how do canine and molar differ.​

Answers

Answer:

Canine teeth is conical in structure and it is used to tear meat but the molar teeth has two or three cusps and is used for grinding food

Nguyên nhân gây bệnh quáng gà ở người là do:đâu

Answers

Answer:

nearsightedness, or blurred vision when looking at faraway objects cataracts, or clouding of the eye's lens retinitis pigmentosa

Explanation:

How does the central bank Control branch ​

Answers

Answer:

Central banks control and manipulate the national money supply: issuing currency and setting interest rates on loans and bonds.

Explanation:

To ensure a nation's economy remains healthy, its central bank regulates the amount of money in circulation. Influencing interest rates, printing money, and setting bank reserve requirements are all tools central banks use to control the money supply.

What are the two main phases of the cell cycle

Answers

Answer:

interphase and the mitotic (M) phase.

Explanation:

The stages of the cell cycle are divided into two major phases: interphase and the mitotic (M) phase.

Answer:

The interphase & the miotic phase

Explanation:

At which location is contact metamorphism least likely to occur

1. divergent boundary
2. convergent boundary
3 .transform boundary

Answers

I say it’s transform boundary

Contact metamorphism is the result of rising of hot magma, where by contact, other previously solidified rocks also metamorphize. This events occurs in convergent and divergent plate boundaries.

-------------------------------------

Contact metamorphism refers to a localized metamorphism. It occurs in the vicinity of intrusive igneous rocks and results from the term effects of hot magma.

Contact metamorphism occurs under elevated temperatures and low-pressure conditions. It is closely related to magmatism.

It occurs in oceanic dorsals, where the extremely hot magma rising to the surface metamorphizes other previously solidified magmatic rocks.

It is very common to find this metamorphism at both convergent and divergent plate boundaries, where molten rock is produced.

I. Convergent. Collision area between two plates. Two oceanic plates might collide, or one oceanic plate with a continental one. In this last case, the oceanic crust sinks under the continental plate, and magma rises to the surface by crevices. The thicker and older plate subduces under the other plate. Also, collisions create volcanic arches and continental arches. In these boundaries, blueschists form by contact and regional metamorphisms.

II. Divergent: New crust is created by the rising molten materials coming from the mantle when two plates separate. A stream of hot material creates a new seabed between the separating plates, producing the sea bottom expansion. This process occurs along with an underwater mountain range, known as the mid-oceanic ridge or divergent ridge. Chlorite and plagioclase metamorphic rocks are formed by contact metamorphism.

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black coffee has a pH of 5, therefore its H+ concentration is ______ times greater than a solution with a pH of 10.

Answers

Answer:

100,000

Explanation:

pH of coffee = 5

pH of solution = 10

Concentration of H+ ions between successive pH values are in multiples of 10

Hence, the pH difference :

pH of solution - pH of coffee

(10 - 5) = 5

Hence, difference in H+ ions will be :

10^5 = 10*10*10*10*10 = 100,000 times

A thermometer is placed in water in order to measure the water’s temperature. What would cause the liquid in the thermometer to drop?

Answers

Answer:

The molecules in the water spread apart. The molecules in the thermometer's liquid spread apart. When a thermometer was placed in water to measure the water’s temperature. the molecules in the thermometer liquid which is often mercury spreads apart and rises, this shows a temperature increase in the thermometer.

DNA is a nucleic acid involved in heredity, or the passing down of genetic traits from one generation to the next. DNA consists of four different types of nucleotide monomers.Which part of the nucleotides' structure is responsible for the incredible variation that exists amongst all types of organisms

Answers

Nitrogenous base DNA consists of four unique nucleotides that each contain one unique nitrogenous base—adenine (A), thymine (T), cytosine (C), or guanine (G).

The specific arrangement of these four bases within the DNA of each organism gives that organism its unique traits; here are the arrangements:

-Adenine is paired with Thymine (think of A for apple and T for tree)

-Cytosine is paired with Guanine (think of C for car and G for garage)

search "DNA base pairs" and go to images for better understanding

The part of the nucleotides' structure is responsible for the incredible variation that exists among all types of organisms are Nitrogenous base DNA consists of four unique nucleotides that each contain one unique nitrogenous base—adenine (A), thymine (T), cytosine (C), or guanine (G).

Who is responsible for passing down of genetic traits from one generation to the next?

DNA is a nucleic acid involved in heredity, or the passing down of genetic traits from one generation to the next. DNA consists of four different types of nucleotide monomers.

The specific arrangement of these four bases within the DNA of each organism gives that organism its unique traits and here are the arrangements are mentioned below:

Adenine is paired with Thymine (think of A for apple and T for tree)Cytosine is paired with Guanine (think of C for car and G for garage)

Therefore, The part of the nucleotides' structure is responsible for the incredible variation that exists among all types of organisms are Nitrogenous base DNA consists of four unique nucleotides that each contain one unique nitrogenous base—adenine (A), thymine (T), cytosine (C), or guanine (G).

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Anaerobic Respiration of Yeast
1. Describe at least one part of the experiment procedure you thought was
essential for getting good results. Did you find that certain steps in the
procedure had to be followed carefully to get consistent results? If you wanted
better results, do you think there is a step that could have been added to the
procedure?
2. Discuss your thoughts on the overall lab design. Did it help you understand the
concepts better, or did it raise more questions? Do you think you could have
designed a better experiment? If so, explain how and then discuss it with your
classmates. Share some of your knowledge with them to learn a little more
about this experiment.

Answers

Anaerobic respiration of yeast produces ethanol and carbon dioxide, which can be experimentally tested by determining the rate of CO2 production in a closed system.

What is anaerobic respiration?

Anaerobic respiration is a series of chemical reactions by which certain organisms can produce energy (ATP) in absence of oxygen.

Anaerobic respiration is useful in experimental settings to determine the survival rate of yeast, which can be determined by measuring the concentration of products of this process.

The experimental procedure requires the use of a closed system to determine the rate of change between reactants (glucose) and products (ethanol + carbon dioxide).

In conclusion, Anaerobic respiration can be experimentally tested by determining the rate of CO2 production.

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The rate of capillary filtration and reabsorption are increased when......... .
A) the negative pressure of interstitial fluid is reduced
B) the pressure of oxygen available to tissues is decreased
C) intravenous pressure is increased

Answers

Answer:

Mechanisms of enhanced transcapillary filtration in response to elevations in arterial or venous pressure. Elevations in arterial (Pa) or venous (Pv) pressure increase capillary pressure, which favors enhanced capillary filtration (Jv).

option"c"

Which statement is not true about the field of science?
it is based on observations and explanations of the natural world.

Answers

You are right with your answer please

Actual Question:
Which statement about the purpose of the field of science is false? (1 point)

Science is used to investigate the natural world.

Events of the natural world can be explained by science.

Science works to establish a collection of unchanging truths.

Useful predictions come from derived explanations of science.
Answer:

Science works to establish a collection of unchanging truths.

Explanation:

I took the test

Aquatic biomes: Briefly describe some of the characteristics of each of the following: Lakes, Wetlands, Estuaries, Intertidal zones, Coral reefs.

Answers

Explanation:

lakes is large in its wide and stagnant water from different water bodies like river, wetlands

what is DNA fingerprinting?​

Answers

Answer:

DNA fingerprinting is a technique that simultaneously detects lots of minisatellites in the genome to produce a pattern unique to an individual. This is a DNA fingerprint. The probability of having two people with the same DNA fingerprint that are not identical twins is very small.,,,,,

Answer:

It's a laboratory technique used to establish a link between biological evidence and a suspect in Criminal investigation. It's also known as genetic fingerprinting.

Basidia within a basidiocarp are obvious for mushrooms, but this may not be as obvious for other examples that you have observed. For each of the examples of basidiomycetes that you have observed, speculate about the location of structures analogous to the basidia observed in mushrooms. Think about the formation of spores by meiosis.

a. bird's-nest fungi
b. common puffballs
c. earthstar puffball
d. shelf fungi
e. corn smut

Answers

Answer:

Birds nest fungi: Basidicarp, a cup shaped with several lenticular bodies appear as bird's nest with eggs. The eggs are called the peridioles and the nest serves release the eggs onto the twigs or branches and spores are liberated .

common puffball: The young fruit body is covered with whitish spines that become mark of scar after maturity.

Earth star puff balls: The fruiting body is in the shape of an egg, it has an outer part that separates away from the inner basidiocarp and splits into several rays which curve backwards and resembles a star.

shelf fungi: The fruiting body develops on the tree trunks and termed conk which are tough and leathery often plate-like growing out of the tree trunks.  

corn smut: The diploid teliospores germinate and undergo meiosis to result in four haploid basidiospores.

what is a structure on a hawk that allows it to survive in its environment and how

Answers

Answer:

Hawks have many adaptations that enable them to survive in high places.

Explanation:

They have hollow bones that gives them buoyancy for flight.

They have good eyesight for hunting prey.

They have feathers to keep them warm during cold weathers. The feathers also add to their ability of flight.

They have claws or talons for attacking prey. They have sharp beaks for tearing into the flesh of their prey.

what is psychasthenia? Please don't copy and paste from g,o,o,g,l,e.

Answers

Answer:

Psychasthenia is a neurotic state characterized especially by phobias, obsessions, or compulsions that one knows are irrational.

what is the difference of biology and human and social biology ???​

Answers

Answer:

Biology is the branch of science.

Human biology is the branch of biology that focuses on human beings and human population.

Social biology is the branch of biology that is the study of social behaviour of animal and human.

Answer:

Biology is the study of living things.

Social biology studies human and animal behaviour.

:):):):):):):):):):):):):):):):):):):):):):):)

Explanation:

In Gregor Mendel's work with pea plants, he found that when a tall pea plant, with genes TT, was crossed with a short pea plant, with genes tt, that _____ % of the first generation of offspring plants were _____.

Answers

Answer:

In Gregor Mendel's work with pea plants, he found that when a tall pea plant, with genes TT, was crossed with a short pea plant, with genes tt, that _100_ % of the first generation of offspring plants were tall pea plant_.

Explanation:

After crossing the two types of plants, Mendel observed that among the F1 there were only tall variants, while the other variant (short) disappeared. Mendel named "dominant" the expressed variant. Mendel then let these new plants auto pollinate and observed the results in the second generation, F2. He saw that the short variant that had previously disappeared, reappeared again. Both tall and short plants were present in the F2. Mendel named "recessive" the second alternative variant.

Mendel explained his results by arguing that discrete factors were responsible for these phenotypes. These factors should have been present in the F1 in pairs. One of them came from one parental plant, and the other factor came from the other plant. These factors then separated again when sex cells were produced, giving two types of gametes, each with only one factor.

Mendel concluded that each plant had a pair of factors -which he named alleles-, and that each factor coded for one trait -tall and short-. He thought that these factors -T and t- separate -segregate- during gamete formation. This conclusion is known as the segregation principle (First Mendels´ Low).

What is the relationship between coronary artery disease and a heart attack?
A. Coronary artery disease is a symptom of heart attacks.
B. Heart attacks reduce blood flow to the heart and cause coronary artery disease.
C. Coronary artery disease can reduce blood flow to the heart and cause heart attacks.
D. Heart attacks occur when coronary artery disease is treated.

Answers

C) Coronary artery disease can reduce blood flow to the heart and cause heart attacks

CAD (or atherosclerosis) affects the vessels that supply blood to the heart muscle. It is caused by deposits of calcium, fat, cholesterol and fibrous tissues, which makes the lumen of arteries narrower. And due to inadequate supply of blood, the heart muscles get damaged. This can lead to a heart attack!


Fermentation preserves food and retains its original flavor as well as increasing its shelf life

Answers

Answer:

Yes it does

Explanation:

true that is facts it sure does

With increases in CO2 in the atmosphere, _______ are expected to experience the largest temperature increases, while __________ are expected to experience the least.

Answer choices
high latitude oceans; high latitude land surfaces
high latitude land surfaces; low latitude oceans
low latitude oceans; high latitude oceans
low latitude land surfaces; high latitude landsurface

Answers

Answer:

The first option would be the best.

Explanation:

The oceans heat up first before the atmosphere does.

What is the correct order of amino acid if the sequence of bases on DNA were as follows: C-C-T-C-G-A-T-T-C-A-T-G
glycine, alanine, lysine, tyrosine

2)

alanine, proline, lysine, tyrosine

3)

valine, aspartate, glycine, proline

4)

aspartate, glycine, serine, valine

Answers

Answer:

it should be G-G-A-G-C-T-A-A-G-T-G-C

Explanation:

A=T

C=G

think of them as opposites. invert them and you'll have the answer (its easier if you write the answer right underneath)

The amino acid sequence should be G-G-A-G-C-T-A-A-G-T-G-C

G-G-A: glycine

G-C-T: alanine

A-A-G: lysine

T-G-C:  tyrosine

What are amino acids?

Amino acids are molecules that combine to form proteins. Amino acids and proteins are the building blocks of life.

The nucleotide triplet that encodes an amino acid is called a codon. Each group of three nucleotides encodes one amino acid. There are 64 combinations of 4 nucleotides taken three at a time and only 20 amino acids, the code is degenerate (more than one codon per amino acid, in most cases).

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In mitosis, the results are 2 different haploid cells.
ASAP please!!!

Answers

Answer:

In mitosis, the results are 2 different diploid cells.

Explanation:

Mitosis is an exact replication of the parent cells, making them diploid cells. 4 haploid cells are the result of meiosis.

Answer:

When a haploid cell undergoes mitosis, it produces two genetically identical haploid daughter cells; when a diploid cell undergoes mitosis, it produces two genetically identical diploid daughter cells. ... In contrast, meiosis is considered a “reductional” form of cell division that occurs in diploid germ cells.

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